8:00 a.m.

Registration and Continental Breakfast

8:50 a.m.

Welcome
Dr. Robert A. Weinberg, Member, Whitehead Institute Director, Ludwig Center for Molecular Oncology, MIT

9:00 - 9:40 a.m.

Biodiversity in the human body
Dr. Patrick O. Brown, Department of Biochemistry & Howard Hughes Medical Institute, Stanford University School of Medicine

9:45 - 10:25 a.m.

Dr. Kornelia Polyak, Associate Professor of Medicine, Department of Medical Oncology, Dana-Farber Cancer Institute

10:30 - 11:00 a.m.

11:00 - 11:40 a.m.

Regulation and function of vascular progenitors and modulatory cells in tumor angiogenesis
Dr. Gabriele Burgers, Neill H. and Linda S. Brownstein Endowed Chair in Brain Tumor Research, University of California San Francisco

11:45 - 12:25 p.m.

Tumor microenvironment controls cancer progression and metastasis
Dr. Raghu Kalluri, Harvard Medical School/Beth Israel Deaconess Medical Center

12:30 - 1:45 p.m.

Lunch/Free time

2:00 - 2:45 p.m.

Cancer cell proliferation, metabolism, and differentiation
status proliferation is regulated by O2 availability
Dr. M. Celeste Simon, Professor, Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine

2:50 - 3:30 p.m.

The role of paracrine and juxtacrine signaling in tumorigenesis
Dr. Neil Bhowmick, Assistant Professor
Department of Urologic Surgery, Vanderbilt University Medical Center

3:35 - 4:10 p.m.

How cancer cells trigger inflammation for their own benefit
Dr. Michael Karin, Department of Pharmacology, University of California San Diego

4:15 - 5:10 p.m.

Searching for brain metastasis mediators through functional selection and clinical validation
Dr. Joan Massague, Chairman, Cancer Biology & Genetics, Memorial Sloan-Kettering Cancer Center

5:15 - 5:30 p.m.

Closing Remarks
Dr. Robert A. Weinberg, Whitehead Institute